Category:
Chiral Intermediates
CAS NO:
595-33-5
Standard:
USP,BP,EP,
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smotic Pressure Regulators / Tonicity Adjusting Agents
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Chiral Intermediates
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Ointment Filling-sealing Machine、Vacuum Mixer
Eye Drug Machinery
Soft Gelatin Capsule Machinery
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Granulator
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Tetracycline
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Powder Filling Machine
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Low Temperature Pulverizer
Strapping machine
Paper Film Packaging Machine
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Spectrometers
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Storage Cabinets
Plastic Bottles
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Feed Additives
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Pulverizer
Coating Machine
Capsule Filling Machine
Other Mixing Equipment
Cell Engineering Equipment
Pre-filled Syringe Production Equipment
Purification Equipment
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Regenerative Materials
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Medicine Film Drug Machinery
Infusion Medicine Machinery（中文站有输液剂机械的三级分类）
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Instruction Booklet Folding Machine
Fan
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Gasket
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Lincomycin
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Pen Injector
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Spray Pump
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Coding Machine
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Packaging Bag Valve
Freeze Dryer
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Other Antibiotics
Cap Screwing Machine
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Printing Services
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Labelling
Powder Packaging Machine
Synthesizer
Heat Shrink Packaging Machine
Metal Detector
Insulin Pens / Blood Glucose Management Devices
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Filter Cartridge
Tablet Packaging Machine
Animal Experiment Instrument
Injection & blow molding machines
Batching system
Self-Injection Systems / Safety Protection Devices
Incubator Equipment
Printed Drugs Packaging
Box filling & sealing machine
Palletizing equipment
CIP cleaning system
Topical / Gynecological / Intimate Drug Delivery Devices
Desiccants
Other Life Science Instrument
Bottle Filling Line
Contaners
Lifting Charging Machine
Others
Inhalant Packaging
BFS Bottlepack Machine
Weighting Equipment
Blister Packaging Machine
Pharmaceutical Paper
Other Pharmaceutical Outer Packaging Equipment
Packaging bag valve
Container Sealing Machine
Glass Tube
Multi-functional Bottle Packaging Machine
Medical Aesthetic Freeze-Dried Powder Vials
Sachets Cartoner Packing line
Primary Packaging
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Aluminum Caps & Aluminum-Plastic Combination Caps
Sterile Bags / Breathing Bags / Sterilization Bags
Medical Device Packaging / Bioconsumables Packaging
Dispensing Bottles
Blister Packaging
Pharmaceutical Plastic Films / Composite Film Bags
Accessories
Ampuls
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Basic Info
CAS Number
595-33-5
Pharmacopoeia
USP,BP,EP
Grade
Pharmaceutical Grade
Is Manufacturer
No
Samples Provided
YES
Sample Policy
Free
Packaging & Delivery
Packaging Specification
1kg, 2kg, 5kg, 10kg, 25kg
Minimum Order Quantity
10g
Delivery Cycle
ONE MOUNTH
Product Description
USE TO TREATMENT OF:
Cachexia, Inoperable endometrial carcinoma, Metastatic endometrial carcinoma, Recurrent endometrial carcinoma, Inoperable carcinoma of the breast, Metastatic carcinoma, Recurrent carcinoma, unexplained weight loss, Anorexia, Cachexia, etc.
AI Product Description
*The following content is generated by AI and is for reference only.
Megestrol Acetate is a synthetic progestin derivative widely utilized in clinical medicine for its potent hormonal activity. With the Chemical Abstracts Service (CAS) registry number 595-33-5, this compound features the molecular formula C24H30O4 and a molecular weight of approximately 386.49 g/mol. Structurally, it mimics the natural hormone progesterone but possesses enhanced oral bioavailability and metabolic stability, allowing for effective therapeutic outcomes with standard dosing regimens.
The primary medical applications of Megestrol Acetate focus on two distinct areas: oncology and appetite stimulation. In oncology, it serves as a critical treatment option for advanced metastatic breast cancer and endometrial carcinoma. By interfering with estrogen production and receptor binding, it helps inhibit tumor growth in hormone-sensitive cancers. Additionally, it is frequently prescribed off-label or as an approved therapy to manage severe cachexia and significant unintentional weight loss associated with chronic diseases such as AIDS and certain malignancies. Its ability to stimulate appetite and promote fat deposition makes it invaluable for improving the quality of life in palliative care settings.
Pharmacologically, Megestrol Acetate acts by binding to progesterone receptors, which triggers a cascade of effects including the suppression of gonadotropin secretion and modulation of the hypothalamic-pituitary-adrenal axis. While generally well-tolerated, patients must be monitored for potential side effects, including thromboembolic events, fluid retention, adrenal suppression, and hyperglycemia. Due to its impact on glucose metabolism, diabetic patients require careful management during treatment. The drug is typically administered orally in tablet form, with dosages varying significantly based on the specific indication and individual patient response.
In summary, Megestrol Acetate remains a cornerstone in the management of hormone-dependent cancers and wasting syndromes. Its unique pharmacological profile offers clinicians a versatile tool to address both disease progression and symptom management. Continued research ensures its optimal integration into treatment protocols, balancing efficacy with safety considerations for diverse patient populations requiring long-term hormonal therapy.
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