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Products

Chiral Intermediates

4-Toluenesulfonylurea

Category:

Chiral Intermediates

CAS NO:

1694-06-0

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East

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Beijing Hope Pharmaceutical Co., Ltd.

Years

Show Room

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Basic Info

CAS Number

1694-06-0

Pharmacopoeia

In-house Standards

Grade

Chemical Grade

Is Manufacturer

YES

Samples Provided

YES

Product Description

Beijing Hope Pharmaceutical Co., Ltd. is a high-tech pharmaceutical company based in China and facing the world. The main business is R&D, production and sales of APIs and APIs, import and export trade, R&D of new pharmaceutical preparations and new drug registration. We have an R&D center in Beijing, a pharmaceutical intermediate production base in Hebei and Zhejiang, and a GMP-certified API production base in Shandong.

AI Product Description

*The following content is generated by AI and is for reference only.

4-Toluenesulfonylurea, also known as p-toluenesulfonylurea or 4-methylbenzenesulfonamide derivative, is a specialized organic compound widely utilized in pharmaceutical research and agrochemical synthesis. With the molecular formula C₇H₉NO₃S and a CAS registry number of 98-06-2, this substance features a sulfonylurea moiety attached to a para-substituted benzene ring containing a methyl group. The molecule exhibits distinct chemical properties arising from its sulfonamide linkage and urea functionality, making it an invaluable intermediate in the construction of more complex heterocyclic systems. In the pharmaceutical industry, 4-Toluenesulfonylurea serves as a critical building block for synthesizing various sulfonylurea-based drugs, which are primarily employed as antidiabetic agents. These compounds function by stimulating insulin secretion from pancreatic beta cells through the inhibition of ATP-sensitive potassium channels. Additionally, due to its structural similarity to many bioactive molecules, it is frequently used in medicinal chemistry laboratories to explore structure-activity relationships (SAR) during drug discovery campaigns. Researchers often employ it as a starting material to introduce specific substituents that modulate potency, selectivity, and metabolic stability. Beyond human medicine, derivatives of this compound find applications in agricultural science, particularly in the development of herbicides. Sulfonylureas are renowned for their high efficacy at low application rates, targeting acetolactate synthase (ALS) enzymes in plants. While 4-Toluenesulfonylurea itself may not be the final active ingredient, it acts as a precursor for creating novel agrochemicals with improved environmental profiles. Its solid-state nature facilitates easy handling and storage, although standard safety precautions regarding skin and eye irritation should always be observed during laboratory manipulation. Overall, 4-Toluenesulfonylurea represents a versatile scaffold in modern synthetic chemistry. Its availability and reactivity allow chemists to efficiently construct diverse molecular architectures essential for advancing therapeutic and agricultural solutions. As research into targeted therapies and sustainable farming continues to evolve, the role of such fundamental intermediaries remains pivotal in bridging theoretical design and practical application across multiple scientific disciplines.