Product Description
Beijing Hope Pharmaceutical Co., Ltd. is a high-tech pharmaceutical company based in China and facing the world. The main business is R&D, production and sales of APIs and APIs, import and export trade, R&D of new pharmaceutical preparations and new drug registration. We have an R&D center in Beijing, a pharmaceutical intermediate production base in Hebei and Zhejiang, and a GMP-certified API production base in Shandong.
AI Product Description
*The following content is generated by AI and is for reference only.
Vortioxetine Hydrobromide (HBr) is a novel multimodal antidepressant agent widely utilized in the clinical management of Major Depressive Disorder (MDD). Chemically, it serves as the hydrobromide salt form of vortioxetine, enhancing its solubility and bioavailability for pharmaceutical formulation. The molecular formula of this compound is C19H24N3O2S·HBr, reflecting its complex structure which includes a thiomorpholine ring and a benzothiophene moiety. Its unique mechanism of action distinguishes it from traditional selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs). Vortioxetine acts not only by inhibiting the serotonin transporter (SERT) but also by modulating multiple serotonin receptor subtypes, including acting as an agonist at 5-HT1A receptors and an antagonist at 5-HT3, 5-HT1D, 5-HT7, and 5-HT1B receptors. This multifaceted profile facilitates the release of other neurotransmitters such as norepinephrine, dopamine, acetylcholine, and glutamate in specific brain regions, potentially offering superior efficacy in improving cognitive dysfunction associated with depression.
The CAS number for Vortioxetine HBr is 847956-03-8, a critical identifier for regulatory compliance, inventory management, and chemical research globally. Approved by major health authorities including the FDA and EMA, it is marketed under various brand names to treat adults suffering from MDD. Clinical studies suggest that beyond alleviating core depressive symptoms like low mood and anhedonia, vortioxetine may provide distinct benefits in restoring cognitive functions, such as attention, memory, and executive processing speed, which are often impaired in depressed patients. Common side effects include nausea, vomiting, constipation, and dry mouth, though these are generally manageable. As a prescription medication, it represents a significant advancement in psychopharmacology, addressing both affective and cognitive dimensions of mental illness. Its development underscores the shift towards targeted therapies that offer comprehensive symptom relief, making it a valuable asset in modern psychiatric treatment protocols worldwide.