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CAS NO:
134404-52-7
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Basic Info
CAS Number
134404-52-7
Pharmacopoeia
ChP,USP,BP,EP,JP,ChP
Product Keywords
Seocalcitol ,,Intermediates
Is Manufacturer
No
Samples Provided
NO
Packaging & Delivery
Packaging Specification
packaging :
shipping_port :
shipping_port :
Product Description
AI Product Description
*The following content is generated by AI and is for reference only.
Seocalcitol, chemically known as 19-nor-24-oxa-1,25-dihydroxyvitamin D3, is a synthetic analog of active vitamin D with a distinct structural modification where the C-24 carbon atom is replaced by an oxygen atom. This unique alteration significantly enhances its metabolic stability and biological activity compared to natural calcitriol. The compound is widely recognized for its potent regulation of calcium and phosphorus homeostasis, making it a critical therapeutic agent in managing disorders related to bone metabolism. Its primary clinical application involves the treatment of secondary hyperparathyroidism in patients undergoing chronic hemodialysis, particularly those suffering from end-stage renal disease. By binding to vitamin D receptors with high affinity, Seocalcitol suppresses parathyroid hormone secretion, thereby preventing bone resorption and reducing the risk of vascular calcification associated with mineral imbalances.
The molecular formula of Seocalcitol is C27H46O2, reflecting its complex steroid backbone modified by the ether linkage at position 24. While specific CAS registry numbers may vary slightly depending on the salt form or regional database classification, the core structure remains consistent across pharmaceutical preparations. Beyond its established role in nephrology, research continues to explore its potential in oncology due to its ability to induce cell differentiation and apoptosis in certain cancer cell lines, although these applications remain largely investigational. Unlike some other vitamin D analogs, Seocalcitol exhibits a favorable safety profile regarding hypercalcemia, allowing for more flexible dosing regimens in clinical settings. It is typically administered orally or via intravenous infusion under strict medical supervision to ensure optimal therapeutic outcomes. As a next-generation vitamin D derivative, Seocalcitol represents a significant advancement in treating complex metabolic bone diseases, offering clinicians a powerful tool to improve patient quality of life while minimizing adverse effects linked to traditional therapies. Ongoing studies aim to further elucidate its mechanism of action and expand its utility in broader metabolic contexts.
![4-[[[[6-[(Diethylamino)methyl]-2-naphthalenylmethoxy]carbonyllaminolbenzoic acid](https://eimg.pharmasources.com/image/20241206/xJCFsdgfMrHzqjtgeOixhGQHgVbKi7kAcoEqemzE.jpg)
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