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Basic Info
CAS Number
/
Pharmacopoeia
In-house Standards
Grade
Research grade
Is Manufacturer
No
Samples Provided
YES
Sample Policy
1-10mg for free
Packaging & Delivery
Packaging Specification
500mg,1g, 10g,50g 100g per package with icebag
Minimum Order Quantity
10mg
Delivery Cycle
In stock or 2-3 weeks
Product Description
Hangzhou Go Top Peptide Biotech Co., Ltd. is a national high-tech enterprise specializing in the research and development and production of peptides and related derivatives. It provides peptide-related custom synthesis and technology for domestic and foreign medical research and development, biotechnology, universities and scientific research institutions service. For consultation or ordering, please contact:86-571-88211951, 86-13588827304 (Cindy Mei), sales96@gotopbio.com
AI Product Description
*The following content is generated by AI and is for reference only.
Fmoc-Phe-Wang resin is a specialized solid-phase synthesis support widely utilized in the pharmaceutical and chemical research industries for the efficient production of peptide sequences. This reagent consists of F-protected phenylalanine covalently attached to Wang resin via a stable ester linkage. The Wang linker features a 4-hydroxymethylphenoxy group, which facilitates the final cleavage of the synthesized peptide under mild acidic conditions, typically using trifluoroacetic acid (TFA), yielding the free C-terminal carboxylic acid without requiring additional protecting groups on the side chain.
The molecular formula for the active component, Fmoc-L-phenylalanine, combined with the Wang linker structure, generally corresponds to C26H25NO4 when considering the specific attachment unit prior to polymerization, though the full resin composition includes the polystyrene backbone. While specific CAS numbers vary depending on the manufacturer and loading capacity (often ranging from 0.5 to 1.0 mmol/g), the core Fmoc-Phe moiety is associated with CAS 189733-83-3 for the protected amino acid itself, whereas the functionalized resin often carries distinct catalog-specific identifiers. Its primary application lies in automated peptide synthesizers, where it serves as the foundational starting point for building complex biological molecules.
Due to the robustness of the Fmoc protection strategy, this resin allows for selective deprotection using piperidine while maintaining stability against various reaction conditions encountered during elongation cycles. Phenylalanine, being a hydrophobic, non-polar amino acid, makes Fmoc-Phe-Wang resin particularly suitable for synthesizing peptides requiring specific structural motifs or membrane-interacting domains. Researchers frequently employ this material to create drug candidates, enzyme inhibitors, and diagnostic markers. The ease of purification resulting from the clean cleavage profile significantly reduces downstream processing time and cost. Furthermore, the high loading capacities available ensure efficient yields even for difficult sequences prone to aggregation. As a critical tool in modern combinatorial chemistry, Fmoc-Phe-Wang resin remains indispensable for accelerating the discovery of novel therapeutic agents and understanding fundamental protein interactions within the life sciences community.
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