Product Description
Hangzhou Go Top Peptide Biotech Co., Ltd. is a national high-tech enterprise specializing in the research and development and production of peptides and related derivatives. It provides peptide-related custom synthesis and technology for domestic and foreign medical research and development, biotechnology, universities and scientific research institutions service. For consultation or ordering, please contact:86-571-88211951, 86-13588827304 (Cindy Mei), sales16@gotopbio.com
AI Product Description
*The following content is generated by AI and is for reference only.
Fmoc-Phe-OH, chemically known as N-(9-fluorenylmethoxycarbonyl)-L-phenylalanine, is a fundamental building block in modern solid-phase peptide synthesis (SPPS). With the molecular formula C23H19NO4 and a CAS number of 71905-46-7, this compound serves as a protected amino acid derivative essential for constructing complex polypeptide chains. The molecule consists of a phenylalanine residue where the alpha-amino group is shielded by a fluorenylmethyloxycarbonyl (Fmoc) protecting group. This specific protection strategy is highly valued in organic chemistry because the Fmoc group can be removed under mild basic conditions, typically using piperidine or diethylamine, without affecting acid-sensitive side-chain protections like Boc or t-butyl esters.
In pharmaceutical research and biotechnology, Fmoc-Phe-OH is indispensable for the efficient synthesis of therapeutic peptides, including insulin analogs, antimicrobial agents, and hormone mimetics. Its high purity is critical for ensuring the correct folding and biological activity of the final peptide product. The reagent facilitates automated peptide synthesizers, allowing for rapid assembly of sequences with high fidelity. Furthermore, its stability during storage and ease of handling make it a preferred choice for both academic laboratories and industrial manufacturing facilities. Researchers utilize this compound to introduce phenylalanine residues into various positions within a peptide backbone, contributing significantly to protein structure studies and drug discovery programs. The versatility of Fmoc chemistry enables the creation of diverse peptidomimetics and cyclic peptides that are often difficult to synthesize using traditional methods. As the demand for novel peptide-based therapeutics grows, the role of Fmoc-Phe-OH remains central to advancing medicinal chemistry. It continues to be a standard reagent in global supply chains, supporting innovations in vaccine development, enzyme inhibitors, and diagnostic tools. Ultimately, this versatile chemical agent bridges the gap between simple amino acids and complex bioactive molecules, driving progress in life sciences.