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Amino Acids and Derivatives
CAS NO:
71989-26-9
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Basic Info
CAS Number
71989-26-9
Pharmacopoeia
In-house Standards
Grade
Research grade
Is Manufacturer
No
Samples Provided
YES
Sample Policy
1-10mg for free
Packaging & Delivery
Packaging Specification
500mg,1g, 10g,50g 100g per package with icebag
Minimum Order Quantity
10mg
Delivery Cycle
In stock or 2-3 weeks
Product Description
Hangzhou Go Top Peptide Biotech Co., Ltd. is a national high-tech enterprise specializing in the research and development and production of peptides and related derivatives. It provides peptide-related custom synthesis and technology for domestic and foreign medical research and development, biotechnology, universities and scientific research institutions service. For consultation or ordering, please contact:86-571-88211951, 86-13588827304 (Cindy Mei), sales3@gotopbio.com
AI Product Description
*The following content is generated by AI and is for reference only.
Fmoc-Lys(Boc)-OH is a critical protected amino acid building block widely utilized in the field of peptide synthesis and medicinal chemistry. Its molecular formula is C23H26N2O7, and it bears the CAS Registry Number 15694-04-9. This compound represents a specific derivative of L-lysine where the alpha-amino group is protected by a 9-fluorenylmethoxycarbonyl (Fmoc) group, while the epsilon-amino group on the side chain is safeguarded by a tert-butyloxycarbonyl (Boc) group. The carboxylic acid moiety remains free, facilitating standard coupling reactions to form peptide bonds.
The primary application of Fmoc-Lys(Boc)-OH lies in solid-phase peptide synthesis (SPPS), particularly within the Fmoc/t-Bu strategy. In this methodology, the Fmoc group serves as an orthogonal protecting group that can be selectively removed using mild bases like piperidine without affecting the acid-labile Boc group on the lysine side chain. This orthogonality is essential for constructing complex peptides containing multiple lysine residues or other sensitive functional groups. Researchers utilize this reagent to synthesize therapeutic peptides, enzyme inhibitors, vaccine candidates, and bioactive molecules where precise control over lysine functionality is required. The Boc protection ensures that the side-chain amine does not participate in unwanted side reactions during the elongation of the peptide chain, thereby maintaining high purity and structural integrity of the final product.
Furthermore, Fmoc-Lys(Boc)-OH is valued for its stability under standard storage conditions and its solubility in common organic solvents such as dimethylformamide (DMF) and dichloromethane. It plays a pivotal role in the development of novel pharmaceuticals, including those targeting cancer, infectious diseases, and metabolic disorders. By enabling the efficient assembly of sequences with specific lysine modifications, this building block supports advancements in drug discovery and protein engineering. Its commercial availability in high purity grades makes it a staple for both academic laboratories and industrial manufacturing processes focused on producing high-value biopharmaceuticals. Ultimately, Fmoc-Lys(Boc)-OH remains an indispensable tool for chemists aiming to create sophisticated peptidic structures with defined biological activities.
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