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CAS NO:
35661-39-3
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Basic Info
CAS Number
35661-39-3
Pharmacopoeia
In-house Standards
Grade
Research grade
Is Manufacturer
No
Samples Provided
YES
Sample Policy
1-10mg for free
Packaging & Delivery
Packaging Specification
500mg,1g, 10g,50g 100g per package with icebag
Minimum Order Quantity
10mg
Delivery Cycle
In stock or 2-3 weeks
Product Description
Hangzhou Go Top Peptide Biotech Co., Ltd. is a national high-tech enterprise specializing in the research and development and production of peptides and related derivatives. It provides peptide-related custom synthesis and technology for domestic and foreign medical research and development, biotechnology, universities and scientific research institutions service. For consultation or ordering, please contact:86-571-88211951, 86-13588827304 (Cindy Mei), sales22@gotopbio.com
AI Product Description
*The following content is generated by AI and is for reference only.
Fmoc-Ala-OH, chemically known as N-(9-Fluorenylmethoxycarbonyl)-L-alanine, is a fundamental building block widely utilized in modern solid-phase peptide synthesis (SPPS). Its molecular formula is C18H17NO4, and it carries the CAS registry number 63250-26-4. This compound serves as a protected amino acid derivative where the alpha-amino group of L-alanine is safeguarded by the fluorenylmethyloxycarbonyl (Fmoc) group. This specific protecting strategy is highly valued because the Fmoc group is base-labile, allowing for its removal under mild alkaline conditions, typically using piperidine, without affecting other acid-sensitive side-chain protecting groups often employed in complex peptide assembly.
The primary application of Fmoc-Ala-OH lies in the automated or manual synthesis of peptides on resin supports. Due to the stability of the alanine side chain and the robustness of the Fmoc group during standard coupling cycles, this reagent is essential for constructing peptides ranging from short oligomers to larger therapeutic sequences. It ensures high fidelity and purity by preventing premature polymerization or racemization during the elongation process. Furthermore, its solubility properties make it compatible with common organic solvents like dimethylformamide (DMF) and dichloromethane (DCM), facilitating efficient reaction kinetics.
In pharmaceutical research, Fmoc-Ala-OH is a critical component for developing bioactive peptides, including enzyme inhibitors, antimicrobial agents, and potential vaccine candidates. The versatility of the Fmoc chemistry allows for the incorporation of this residue into diverse structural motifs while maintaining stereochemical integrity. Beyond academic laboratories, it is also used in industrial settings for the large-scale production of peptide drugs and diagnostic markers. Researchers rely on high-purity batches of Fmoc-Ala-OH to minimize byproduct formation and simplify downstream purification steps, ultimately ensuring the reliability of their experimental data. As peptide therapeutics continue to gain prominence in medicine, the demand for reliable, high-quality Fmoc-protected amino acids remains paramount for advancing drug discovery and development pipelines globally.
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