Category:
Chiral Intermediates
CAS NO:
313-06-4
Standard:
USP,
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Basic Info
CAS Number
313-06-4
Pharmacopoeia
USP
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Samples Provided
YES
Sample Policy
5-10g free sample
Packaging & Delivery
Delivery Cycle
5Days
Product Description
Estradiol Cypionate is a sex hormone. Estradiol Cypionate is the predominant sex hormone present in females. It is also present in males, being produced as an active metabolic product of testosterone. It represents the major estrogen in humans. Estradiol has a critical impact on reproductive and sexual functioning.
AI Product Description
*The following content is generated by AI and is for reference only.
Estradiol Cypionate is a potent synthetic estrogen derivative widely utilized in medical and veterinary practices. Chemically, it is an ester of estradiol with cyclopentanepropionic acid, designed to prolong the duration of action compared to native estradiol. Its molecular formula is C23H32O3, and it is identified by the CAS number 57-63-6. This compound functions as a long-acting prodrug; once administered via intramuscular injection, esterases slowly hydrolyze the cypionate moiety, releasing active estradiol into the bloodstream over an extended period, typically lasting several weeks.
The primary clinical application of Estradiol Cypionate is hormone replacement therapy (HRT) for postmenopausal women. It effectively alleviates vasomotor symptoms such as hot flashes and night sweats, treats vaginal atrophy, and helps prevent osteoporosis associated with estrogen deficiency. Furthermore, it plays a critical role in gender-affirming hormone therapy for transgender women, where it serves as a cornerstone treatment to induce and maintain secondary female sexual characteristics. In veterinary medicine, this compound is occasionally employed to manage reproductive disorders in animals, including conditions like pyometra or estrus suppression, though regulatory approval varies significantly by region.
Pharmacokinetically, the lipophilic nature of the cypionate ester allows for slow absorption from the injection site, ensuring stable serum estrogen levels and reducing the frequency of required dosing. However, its use necessitates careful medical supervision due to potential side effects, which may include nausea, breast tenderness, fluid retention, and an increased risk of thromboembolic events or cardiovascular complications. Patients with a history of hormone-sensitive cancers, liver disease, or unexplained vaginal bleeding are generally contraindicated for this therapy. While highly effective when prescribed correctly, strict adherence to dosage guidelines and regular health monitoring are essential to maximize therapeutic benefits while minimizing adverse outcomes. As a controlled substance in many jurisdictions, it must be dispensed solely through licensed healthcare providers following comprehensive patient evaluation.
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