vitaminK1chromenol;VitaminK1ChromenolImpurityQ:WhatisVitaminK1ChromenolImpurityQ:WhatistheCASNumberofVitamChemicalbookinK1ChromenolImpurity;2,5-dimethyl-2-(4,8,12-trimethyltridecyl)-2H-benzo[h]chromen-6-ol;VitaminK1ImpurityG
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<h3>Overview</h3>
<p><strong>Vitamin K1 Impurity G</strong> is a critical reference standard used in pharmaceutical quality control to identify and quantify degradation products during the synthesis of phylloquinone. It serves as an essential marker for assessing purity in active pharmaceutical ingredients (APIs). The compound features a distinct molecular structure characterized by <strong>C<sub>31</sub>H<sub>46</sub>O<sub>2</sub></strong>, with the specific CAS registry number <strong>58-75-9</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical QC:</strong> Employed in HPLC method development to validate the separation efficiency of Vitamin K1 formulations.</li>
<li><strong>R&D Stability Testing:</strong> Utilized to monitor oxidative degradation pathways under stress conditions during shelf-life studies.</li>
<li><strong>Regulatory Compliance:</strong> Provides benchmark data for ICH guidelines regarding impurity profiling in drug substance dossiers.</li>
</ul>
<h3>Precautions</h3>
<p>This material requires storage in sealed containers at <strong>-20°C</strong> under inert atmosphere to prevent oxidation. Handling must occur within a certified fume hood using appropriate PPE, as direct skin contact may cause sensitization. Strict adherence to local hazardous waste disposal regulations is mandatory.</p>