HOYWIHISJSBZLW-JTQLQIEISA-N;L-Glutamicacid,N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)carbonyl]amino]benzoyl]-(9CI);FolicAcidImpurity40;2-(4-(2-Amino-4-Chemicalbookoxo-3,4-dihydropteridine-6-carboxamido)benzamido)pentanedioicacid;Folicacidoxidizesimpurities;CalciumLevofolinateImpurity19;9-OxofolicAcid;FolicAcidImpurityL
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Calcium Levofolinate Impurity</strong> refers to chemical variants or byproducts associated with the synthesis of calcium levofolinate, a leucovorin calcium salt used in oncology. Its core molecular formula is typically <strong>C20H18CaN8O7</strong>, with specific CAS numbers varying by structural isomer.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical Quality Control: Used as reference standards for HPLC analysis during drug substance manufacturing.</li>
<li>R&D Development: Essential for method validation and impurity profiling in clinical trial materials.</li>
<li>Regulatory Compliance: Required for submitting impurity data dossiers to FDA and EMA authorities.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at 2-8°C to prevent degradation. Handle with appropriate PPE as a potential mutagenic agent; strictly avoid inhalation or skin contact during laboratory operations.</p>