1R-Dapagliflozin;DapagliflozinImpurity77;Dapagliflozin-1;Dapagliflozinimpurity26/1R-Dapagliflozin/DapagliflozinAlphaIsomer/(2R,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzylChemicalbook)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;Dapagliflozinalpha-Isomer;Alpha-IsomerofDapagliflozin;DapagliflozinAlphaisomer(Crude);DapagliflozinalphaisomerI
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<h3>Overview</h3>
<p>Dapagliflozin Impurity A is a critical reference standard for the pharmaceutical analysis of the SGLT2 inhibitor. Synthesized via specific coupling routes, it serves as an identification marker for process control. The compound features the molecular formula <strong>C18H26O7</strong> and CAS number <strong>149209-65-2</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Quality Control:</strong> Used in HPLC methods to identify and quantify related substances during drug substance manufacturing.</li>
<li><strong>Method Validation:</strong> Employed to establish specificity and sensitivity limits for regulatory submission dossiers.</li>
<li><strong>R&D Studies:</strong> Applied in stability testing to monitor degradation pathways under various stress conditions.</li>
</ul>
<h3>Precautions</h3>
<p>Store in sealed containers at <strong>-20°C</strong> protected from light and moisture. Handle with appropriate PPE to avoid inhalation or skin contact. This material is strictly for laboratory research use only and not intended for clinical administration.</p>