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CAS NO:
105832-38-0
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Basic Info
CAS Number
105832-38-0
Pharmacopoeia
In-house Standards
Grade
Research grade
Is Manufacturer
No
Packaging & Delivery
Packaging Specification
5g,10g,25g,50g,100g,500g
Minimum Order Quantity
5g
Delivery Cycle
In stock or 1-3weeks
Product Description
Hangzhou Go Top Peptide Biotech Co.,Ltd. - a reliable supplier of peptides synthesis.Our clients include * the pharma, cosmetic and biotech companies and research institutions worldwide. Welcome to contact us by email to sales13@gotopbio.com
AI Product Description
*The following content is generated by AI and is for reference only.
TSTU, chemically known as 1-[(E)-2-(4-toluenesulfonyloxy)ethyl]-3-methylimidazolium tetrafluoroborate or more commonly referred to in specific contexts as a specialized sulfonate ester derivative used in organic synthesis, is a versatile reagent primarily employed for the introduction of imidazole moieties into various substrates. While exact commercial nomenclature can vary slightly depending on the manufacturer and specific application context, TSTU generally denotes a compound featuring a tosylated ethyl chain linked to an imidazolium core, often paired with a non-coordinating anion such as tetrafluoroborate to enhance solubility and stability. The CAS number associated with this specific class of reagents is typically distinct from simple salts, requiring precise identification based on the anion and cation structure; however, in many synthetic databases, related compounds like N-succinimidyl esters or similar activated esters are sometimes conflated under abbreviated codes, necessitating careful verification against supplier catalogs for the exact molecular formula, which usually approximates C16H20BF4N2O3S or similar variations depending on the counterion.
The primary utility of TSTU lies in its role as an efficient coupling agent or alkylating agent in peptide chemistry and medicinal chemistry laboratories. It facilitates the rapid formation of amide bonds or the alkylation of nucleophilic sites on amino acids and peptides under mild conditions, often serving as a superior alternative to traditional carbodiimide reagents due to reduced racemization risks and higher reaction yields. Its high reactivity stems from the excellent leaving group ability of the tosylate moiety, allowing for smooth substitution reactions with amines, thiols, or other heterocyclic bases. Furthermore, TSTU finds applications in the synthesis of complex pharmaceutical intermediates where regioselectivity and stereochemical integrity are paramount. Researchers utilize it to modify protein surfaces or create bioconjugates by attaching functional tags to specific residues. Despite its effectiveness, handling requires standard laboratory safety precautions, including the use of gloves and fume hoods, as the compound may exhibit irritant properties. Overall, TSTU represents a critical tool in modern organic synthesis, enabling chemists to construct intricate molecular architectures with precision and efficiency, thereby accelerating drug discovery and materials science research globally.
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