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<h3>Overview</h3><p>Tris(2-chloroethyl)phosphate-d12 is a deuterated isotopologue of the flame retardant TCEP, serving as a stable internal standard for mass spectrometry quantification. Synthesized via deuteration of ethyl groups during phosphate esterification, its molecular formula is C6H9Cl3D12O4P with CAS No. 867-50-7.</p><h3>Application</h3><ul><li>Analytical chemistry: Used as an isotopic dilution standard in LC-MS/MS for environmental pollutant monitoring.</li><li>Pharmaceutical research: Applied in ADME studies to trace metabolic pathways of organophosphates.</li><li>Quality control: Validates analytical methods for detecting chlorinated phosphates in industrial effluents.</li></ul><h3>Precautions</h3><p>Classified as a potential carcinogen; requires NIOSH-rated respiratory protection and nitrile gloves. Store in airtight containers at 2-8°C away from oxidizers to prevent hydrolysis or thermal decomposition.</p>