Shanghai AQ BioPharma is A leading company specializing on the fluorine containing drug discovery and fluorinated intermediates/chemicalsmanufacture in china。Our feature products including: fluorinated drug intermediate; piperidine; piperazine; pyrrolidine; azaindole,adamantane,azaspiro- and azafused heterocycles etc.
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*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>tert-butyl 4,4-difluoro-3-(hydroxymethyl)piperidine-1-carboxylate</strong> is a specialized fluorinated piperidine intermediate synthesized via Boc-protection of 4,4-difluoro-3-hydroxymethylpiperidine. Its molecular formula is C<sub>10</sub>H<sub>17</sub>NO<sub>3</sub>F<sub>2</sub>. This compound serves as a critical building block for pharmaceutical scaffolds requiring metabolic stability.</p>
<h3>Application</h3>
<ul>
<li>Medicinal chemistry: Synthesis of kinase inhibitors and GPCR modulators.</li>
<li>Agrochemicals: Development of novel fungicides with enhanced bioactivity.</li>
<li>Process research: Precursor for advanced organic synthesis in API manufacturing.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at 2-8°C to prevent hydrolysis. Use appropriate PPE including nitrile gloves and eye protection due to potential skin irritation. Avoid contact with strong oxidizers.</p>