Category:
Prophylactic Biological Products
CAS NO:
14636-12-5
Standard:
ChP,EP,
Indications:
Mechanism of Action: Terlipressin is a prodrug of lysine vasopressin (LVP). Upon administration, it is hydrolyzed to release LVP. LVP then acts on vasopressin V1 receptors, leading to splanchnic vasoconstriction. This helps reduce portal blood flow and pressure, thereby reducing or stopping esophageal variceal bleeding. In the case of HRS, the vasoconstrictive effect helps improve renal function.
Pharmacokinetics:
Form: Terlipressin API is usually available as a white to off-white lyophilized powder.