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Basic Info
CAS Number
-
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
-
AI Product Description
*The following content is generated by AI and is for reference only.
Silymarin is a standardized polyphenolic extract derived from the seeds of the milk thistle plant, *Silybum marianum*. It serves as a potent hepatoprotective agent widely utilized in both traditional medicine and modern clinical practice. The active components of silymarin are flavonolignans, primarily consisting of silybin (silibinin), silychristin, and silydianin. While the exact molecular formula varies depending on the specific constituent within the complex mixture, silybin, the most abundant and bioactive component, has the molecular formula C25H22O10 and corresponds to CAS number 22888-70-6. The entire silymarin extract does not have a single unique CAS number but is often associated with identifiers like 84650-06-6 for specific standardized preparations.
The primary therapeutic application of silymarin centers on liver health. It is extensively prescribed and supplemented to treat various hepatic conditions, including alcoholic liver disease, non-alcoholic fatty liver disease, hepatitis, and toxin-induced liver damage caused by substances like acetaminophen or Amanita phalloides mushroom poisoning. Its mechanism of action involves multiple pathways: it acts as a strong antioxidant by scavenging free radicals, stabilizes cell membranes to prevent toxin entry into hepatocytes, and stimulates protein synthesis to promote liver regeneration. Furthermore, silymarin exhibits anti-inflammatory and antifibrotic properties, helping to reduce scar tissue formation in chronic liver diseases. Beyond its hepatoprotective effects, research suggests potential benefits for metabolic syndrome, diabetes management, and skin protection against UV radiation due to its antioxidant capacity. Silymarin is generally considered safe with a low incidence of side effects, though mild gastrointestinal disturbances may occur in some individuals. It is commercially available in various forms, including capsules, tablets, liquid extracts, and liposomal formulations designed to enhance bioavailability. Due to its efficacy in supporting liver function and detoxification processes, silymarin remains one of the most popular herbal supplements globally, frequently recommended by healthcare professionals as an adjunct therapy for maintaining optimal hepatic wellness.
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