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<h3>Overview</h3>
<p>Sertraline-d3 Hydrochloride is a <strong>stable isotopically labeled internal standard</strong> used primarily in quantitative analysis. It features the deuterium substitution at specific positions to distinguish from the native analyte during mass spectrometry. The molecular formula is C<sup>20</sup>H<sub>19</sub>D<sub>3</sub>Cl<sub>2</sub>N and its CAS number is 146857-66-3.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical QC:</strong> Validation of assay methods for Sertraline purity testing.</li>
<li><strong>Metabolism Studies:</strong> Tracing metabolic pathways in ADME research using LC-MS/MS.</li>
<li><strong>Toxicology:</strong> Quantitative detection in biological fluids for forensic screening.</li>
</ul>
<h3>Precautions</h3>
<p>Store under <strong>-20°C</strong> in a dry, inert atmosphere to prevent hydrolysis. Handle with appropriate PPE as a controlled chemical substance; avoid direct contact and inhalation of dust.</p>