LCZ696,Sacubatril/Valsartan
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Sacubitril/Valsartan is a fixed-dose combination ARNI (<strong>sacubitril</strong> and <strong>valsartan</strong>) used for heart failure. It inhibits neprilysin and blocks angiotensin II receptors. Molecular formula: C<sub>42</sub>H<sub>50</sub>N<sub>6</sub>O<sub>9</sub>. CAS No.: 184576-82-3.</p>
<h3>Application</h3>
<ul>
<li>Cardiovascular therapeutics: Chronic heart failure management with reduced ejection fraction.</li>
<li>Pharmaceutical manufacturing: API production for oral tablets in global markets.</li>
<li>Clinical research: Drug efficacy trials for hypertension and renal protection.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in pregnancy and history of angioedema. Store at controlled room temperature (20-25°C) in dry, light-resistant containers. Avoid exposure to moisture during handling.</p>