Product Description
Pharmaceutical
Raw Materials and Intermediates
AI Product Description
*The following content is generated by AI and is for reference only.
(S)-Cbz-Phenylalaninol is a specialized chiral building block widely utilized in modern organic synthesis and pharmaceutical research. Chemically known as (S)-benzyloxycarbonylphenylalaninol, this compound features a protected amino group via the carbobenzoxy (Cbz) moiety attached to a phenylalanine backbone that has been reduced to its corresponding alcohol. Its molecular formula is C17H19NO3, with a precise molecular weight of 285.34 g/mol. The substance is characterized by its high optical purity, typically maintaining an enantiomeric excess exceeding 99%, which is critical for applications requiring specific stereochemical configurations.
The primary CAS registry number for this reagent is 101956-43-6, ensuring accurate identification across global chemical databases and supply chains. Structurally, the molecule combines the robust protection of the benzyl carbamate group with the versatile hydroxyl functionality of the side chain, making it an ideal intermediate for peptide coupling reactions and asymmetric synthesis. Researchers frequently employ (S)-Cbz-Phenylalaninol as a precursor in the development of bioactive peptides, where the Cbz group prevents unwanted side reactions during multi-step syntheses while allowing for selective deprotection later using catalytic hydrogenation or acid treatment.
In the pharmaceutical industry, this chiral alcohol serves as a key scaffold for constructing complex drug candidates, including potential antiviral agents, protease inhibitors, and novel antibiotic derivatives. Its utility extends to materials science, where it aids in the creation of functionalized polymers with specific biological interactions. The compound is generally supplied as a white crystalline solid or powder, stable under standard laboratory conditions but sensitive to strong acidic environments that might cleave the Cbz protecting group prematurely. Storage recommendations typically involve keeping the material in a cool, dry place away from direct sunlight to maintain integrity. Due to its role in producing high-value therapeutics, demand for high-purity (S)-Cbz-Phenylalaninol continues to grow within academic institutions and commercial biotechnology firms seeking efficient routes to stereodefined molecules. This product remains indispensable for chemists aiming to optimize synthetic pathways with precision and reliability.