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Prophylactic Biological Products

Calcium Dobesilate monohydrate

Category:

Prophylactic Biological Products

CAS NO:

Calcium Dobesilate

Standard:

ChP,BP,EP,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East,Africa

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

Calcium Dobesilate

Pharmacopoeia

ChP,BP,EP

Grade

Pharmaceutical Grade

Is Manufacturer

Packaging & Delivery

Packaging Specification

25kgs carboard drum

Delivery Cycle

asap

Product Description

Calcium Dobesilate monohydrate

AI Product Description

*The following content is generated by AI and is for reference only.

Calcium Dobesilate Monohydrate is a widely utilized pharmaceutical agent primarily indicated for the treatment of chronic venous insufficiency and various microcirculatory disorders. Chemically, it exists as a monohydrate salt of dobesilate acid combined with calcium. Its molecular formula is C12H8CaO9S2·H2O, reflecting its hydrated crystalline structure which ensures stability during storage and administration. The substance is identified by the unique CAS registry number 540-73-6, a critical identifier used globally in regulatory compliance, chemical databases, and supply chain logistics to distinguish it from other calcium salts or sulfonated compounds. The primary therapeutic mechanism of Calcium Dobesilate involves strengthening capillary walls and reducing vascular permeability. It achieves this by inhibiting the formation of leukocyte-derived free radicals and suppressing the release of inflammatory mediators such as histamine and prostaglandins. By enhancing the integrity of the endothelial barrier, it effectively reduces edema, pain, and the sensation of heaviness often associated with venous stasis. Consequently, it is frequently prescribed to manage symptoms like leg cramps, varicose veins, hemorrhoids, and diabetic retinopathy, where microvascular leakage poses a significant risk to tissue health. In clinical practice, the drug is available in oral tablet or capsule formulations, typically dosed three times daily depending on the severity of the condition. Its high bioavailability and rapid onset of action make it a preferred choice over older vasoactive agents for many patients. While generally well-tolerated, mild gastrointestinal disturbances may occasionally occur. Extensive pharmacological studies have confirmed its safety profile when used according to established guidelines, making it a staple in vascular medicine across Europe and Asia. As a specialized chemical entity, Calcium Dobesilate Monohydrate plays a vital role in maintaining microcirculatory homeostasis, offering significant relief for patients suffering from chronic venous and capillary pathologies without causing severe systemic side effects.