*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>(R,S)-Norcotinine</strong> is a racemic nicotine metabolite used primarily in pharmaceutical research. Its molecular formula is C<sub>10</sub>H<sub>12</sub>N<sub>2</sub>O, with CAS No. 15678-42-9. Industrial synthesis typically involves the oxidative demethylation of nicotine derivatives.</p>
<h3>Application</h3>
<ul>
<li><strong>Metabolic Studies:</strong> Serves as a standard marker for nicotine metabolism profiling in toxicology.</li>
<li><strong>Drug Development:</strong> Utilized in screening assays for nicotinic acetylcholine receptor modulators.</li>
<li><strong>Quality Control:</strong> Applied as an analytical reference standard in chromatographic purity testing.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly limit use to laboratory settings; avoid human exposure due to potential toxicity. Store under inert atmosphere at temperatures below -20°C to prevent degradation and maintain stability.</p>