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Other Specialized Reagents

(R)-(+)-2-Chloropropionic acid

Category:

Other Specialized Reagents

CAS NO:

7474-05-7

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

7474-05-7

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

(R)-(+)-2-Chloropropionic acid is a valuable chiral building block widely utilized in the pharmaceutical and agrochemical industries for the synthesis of optically active compounds. With the molecular formula C3H5ClO2 and a CAS registry number of 19784-30-6, this compound exists as the pure dextrorotatory enantiomer of chloropropionic acid. Its specific stereochemistry makes it an indispensable reagent for producing chiral intermediates where precise three-dimensional arrangement is critical for biological activity. The primary application of (R)-(+)-2-chloropropionic acid lies in the manufacturing of modern pharmaceuticals. It serves as a key precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), beta-blockers, and various other therapeutic agents that require specific chirality to function effectively within the human body. Unlike racemic mixtures, using the pure R-enantiomer ensures higher efficacy and often reduces potential side effects associated with the unwanted S-isomer. In the agricultural sector, this chemical is employed in the development of selective herbicides and fungicides, contributing to more sustainable farming practices by targeting specific pest mechanisms while minimizing environmental impact. Chemically, the molecule features a propionic acid backbone substituted with a chlorine atom at the alpha position, creating a reactive site for nucleophilic substitution reactions. This reactivity allows chemists to introduce the chiral propionyl moiety into complex molecular structures through various coupling methods. The substance typically appears as a colorless to pale yellow liquid or low-melting solid, possessing a sharp, pungent odor characteristic of carboxylic acids. Due to its corrosive nature and potential skin irritancy, strict safety protocols must be observed during handling, including the use of appropriate personal protective equipment and proper ventilation. Global supply chains rely on high-purity sources of this enantiomer to meet the rigorous standards of GMP-compliant drug manufacturing. As the demand for stereoselective synthesis grows, (R)-(+)-2-chloropropionic acid remains a cornerstone material for organic chemists aiming to develop next-generation therapeutics with optimized pharmacokinetic profiles. Its versatility continues to drive innovation across multiple sectors of the fine chemical industry.