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Other Specialized Reagents

(R)-(-)-Methyl mandelate

Category:

Other Specialized Reagents

CAS NO:

20698-91-3

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

20698-91-3

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

(R)-(-)-Methyl mandelate is a valuable chiral building block widely utilized in the pharmaceutical and fine chemical industries. With the molecular formula C9H10O3 and a CAS registry number of 657-28-5, this compound represents the optically active methyl ester of mandelic acid. It possesses a specific rotation that distinguishes it from its enantiomer, making it an essential reagent for asymmetric synthesis and stereochemical studies. The molecule features a benzene ring attached to a chiral center bearing both a hydroxyl group and a methoxycarbonyl group, contributing to its unique reactivity profile. In industrial applications, (R)-(-)-methyl mandelate serves primarily as a key intermediate in the production of various bioactive compounds. It is frequently employed in the synthesis of beta-blockers, anti-inflammatory agents, and other therapeutic drugs where precise stereochemistry is critical for biological efficacy. Due to its chiral nature, researchers utilize this ester to resolve racemic mixtures or as a starting material for preparing complex organic architectures with defined three-dimensional structures. Its stability under standard storage conditions allows for easy handling and integration into multi-step synthetic pathways. Beyond drug manufacturing, this compound finds use in the development of chiral catalysts and ligands for organometallic chemistry. The presence of the aromatic ring facilitates pi-stacking interactions, while the functional groups offer versatile sites for further chemical modification. As a high-purity optical isomer, it ensures consistency in research outcomes and product quality in commercial settings. Safety data indicates that while it should be handled with standard laboratory precautions to avoid skin or eye irritation, it does not present extreme hazards when managed correctly. Overall, (R)-(-)-methyl mandelate remains a cornerstone material for chemists seeking to advance stereoselective methodologies and develop next-generation medicinal agents with improved pharmacological profiles.