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<h3>Overview</h3>
<p><strong>Propofol-d17</strong> is a deuterated isotopic standard of the anesthetic agent propofol, synthesized via <strong>deuterium exchange</strong> or <strong>isotopic labeling</strong> for metabolic tracing. Its molecular formula is C18H20O and CAS No. 15964-16-2.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmacokinetic Studies:</strong> Used as an internal standard in LC-MS/MS assays to quantify propofol levels in biological matrices.</li>
<li><strong>Clinical Research:</strong> Facilitates precise analysis of drug metabolism pathways and bioavailability during clinical trials.</li>
<li><strong>Quality Control:</strong> Validates analytical methods for pharmaceutical manufacturing of propofol formulations.</li>
</ul>
<h3>Precautions</h3>
<p>Store under <strong>-20°C</strong> in a dry, inert atmosphere to prevent hydrolysis. Handle with appropriate PPE; while non-toxic itself, it is intended solely for research use and not for human administration.</p>