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CAS NO:
68890-66-4
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Basic Info
CAS Number
68890-66-4
Pharmacopoeia
In-house Standards
Grade
Industrial grade
Is Manufacturer
No
Product Description
Cosmetic raw material
AI Product Description
*The following content is generated by AI and is for reference only.
Piroctone Olamine is a widely recognized active ingredient in the cosmetic and personal care industries, primarily celebrated for its potent anti-fungal and anti-bacterial properties. Chemically known as 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridinone olamine salt, it features the molecular formula C15H28N2O3 and carries the CAS registry number 68890-66-4. This compound is essentially an olamine salt of octopirox, a derivative of pyrithione zinc, offering superior solubility in water compared to its predecessor while maintaining high efficacy against dermatological pathogens.
The primary application of Piroctone Olamine lies in the formulation of anti-dandruff shampoos, conditioners, and scalp treatments. It effectively targets *Malassezia globosa* and *Malassezia furfur*, the yeast species responsible for dandruff, seborrheic dermatitis, and scalp itching. By inhibiting the growth of these microorganisms, it helps restore scalp health and reduces flaking without causing significant irritation. Beyond hair care, this ingredient is increasingly utilized in body washes, facial cleansers, and leave-on lotions designed to manage fungal infections or prevent odor-causing bacterial proliferation on the skin. Its mechanism involves disrupting the cell membrane integrity of fungi, thereby halting their replication cycle.
One of the standout advantages of Piroctone Olamine is its excellent safety profile and mildness. Unlike some older antifungal agents, it exhibits low toxicity and minimal risk of sensitization, making it suitable for sensitive skin types and long-term use. Furthermore, it possesses antioxidant properties that may help protect the scalp from oxidative stress. Regulatory bodies worldwide, including those in the European Union and the United States, have approved its use in rinse-off and leave-on products within specific concentration limits, typically ranging from 0.1% to 1.0%. As consumer demand shifts towards gentle yet effective solutions for scalp hygiene, Piroctone Olamine remains a cornerstone ingredient in modern dermatological formulations, bridging the gap between clinical efficacy and cosmetic elegance.
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