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Prophylactic Biological Products
CAS NO:
1513857-77-6
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Infusion Medicine Machinery（中文站有输液剂机械的三级分类）
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Animal Experiment Instrument
Injection & blow molding machines
Batching system
Self-Injection Systems / Safety Protection Devices
Incubator Equipment
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Box filling & sealing machine
Palletizing equipment
CIP cleaning system
Topical / Gynecological / Intimate Drug Delivery Devices
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Bottle Filling Line
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Lifting Charging Machine
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Inhalant Packaging
BFS Bottlepack Machine
Weighting Equipment
Blister Packaging Machine
Pharmaceutical Paper
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Packaging bag valve
Container Sealing Machine
Glass Tube
Multi-functional Bottle Packaging Machine
Medical Aesthetic Freeze-Dried Powder Vials
Sachets Cartoner Packing line
Primary Packaging
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Aluminum Caps & Aluminum-Plastic Combination Caps
Sterile Bags / Breathing Bags / Sterilization Bags
Medical Device Packaging / Bioconsumables Packaging
Dispensing Bottles
Blister Packaging
Pharmaceutical Plastic Films / Composite Film Bags
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Ampuls
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Basic Info
CAS Number
1513857-77-6
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Product Description
Pemigatinib is a small molecule kinase inhibitor with antitumour activity. It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells. FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide variety of cancers including those of the urinary bladder, breast, ovary, prostate, endometrium, lung, and stomach. Deregulated FGFR signalling pathway can lead the development of oncogenes and tumour-promoting physiological processes, such as cancer cell proliferation, enhanced angiogenesis, and evasion of cell death. In April 2020, pemigatinib was approved by the FDA for the treatment of unresectable locally advanced or metastatic cholangiocarcinoma in previously treated adult patients with a fibroblast growth factor receptor 2 (FGFR2) gene fusion or other rearrangements as detected by an FDA-approved test.
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Copyright 2006-2025 (All Rights Reserved)
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