Product Name: Paricalcitol intermediate
CAS No.: 957214-02-7
Quality Standard: Enterprise standard, content NLT 98%
Main Application: Synthesis of Paricalcitol
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Paricalcitol intermediate-2</strong> is a key synthetic precursor in the manufacturing of Paricalcitol (19-nor-1,25-dihydroxyvitamin D<sub>2</sub>), an active vitamin D analog. The core process involves selective photochemical irradiation and chemical modification of specific steroid derivatives to achieve the required stereochemistry. <strong>Molecular Formula</strong>: C<sub>27</sub>H<sub>40</sub>O<sub>3</sub>; <strong>CAS No.</strong>: 163863-82-1.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical synthesis as a critical building block for renal failure therapies.</li>
<li>Production of medications treating secondary hyperparathyroidism in chronic kidney disease patients.</li>
<li>R&D processes for developing novel calcimimetic agents with reduced hypercalcemia risk.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly controlled storage under inert atmosphere at -20°C to prevent degradation. Handling requires PPE due to potential skin irritation. Clinical use is limited by strict dosage protocols to avoid hypercalcemia and vascular calcification risks.</p>