Product Name: Paricalcitol intermediate
CAS No.: 1227926-70-6
Quality Standard: Enterprise standard, content NLT 98%
Main Application: Synthesis of Paricalcitol
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Paricalcitol intermediate refers to key synthetic precursors used in the industrial manufacturing of <strong>19-nor-2-oxa-1,25-dihydroxyvitamin D3</strong>. The core process involves selective photochemical isomerization and enzymatic hydroxylation. While specific intermediates vary by route, common structures include <strong>C27H44O3</strong> variants. CAS numbers depend on the exact isomer, typically ranging between 160000-180000.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing</strong>: Synthesis of paricalcitol capsules for renal disease management.</li>
<li><strong>API Production</strong>: Bulk drug substance processing for dialysis patients.</li>
<li><strong>R&D Laboratories</strong>: Clinical trial material preparation for metabolic bone disorders.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly controlled as pharmaceutical grade; requires storage at <strong>-20°C</strong> under inert atmosphere. Avoid direct sunlight exposure during handling. Personnel must wear appropriate PPE due to potential sensitization risks associated with vitamin D derivatives.</p>