*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Norfluoxetine Hydrochloride is the primary active metabolite of fluoxetine, a selective serotonin reuptake inhibitor. Produced via oxidative N-demethylation of fluoxetine followed by salt formation, its molecular formula is <strong>C17H18F3NO·HCl</strong> and CAS number is <strong>6504-92-1</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical R&D:</strong> Used as a reference standard for bioequivalence studies.</li>
<li><strong>Metabolic Profiling:</strong> Employed in pharmacokinetic analysis to monitor drug metabolism.</li>
<li><strong>Quality Control:</strong> Serves as an impurity standard in fluoxetine manufacturing.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly controlled due to pharmacological activity; requires storage below 25°C in sealed containers away from light. Handling mandates PPE to prevent inhalation or skin contact.</p>