Product Description
NRC;Nicotinamide Riboside Chloride(NRC);Nicotinamide riboside chloride NR-CL;Nicotinamide riboside chloride;3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride;3-carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride;NR-CL;Nicotinamide ribose chloride
AI Product Description
*The following content is generated by AI and is for reference only.
Nicotinamide Riboside Chloride, identified by the CAS number 23111-00-4, is a potent form of vitamin B3 (niacin) and a critical precursor to nicotinamide adenine dinucleotide (NAD+). Its molecular formula is C11H16ClN2O5. Unlike traditional niacin or nicotinamide, this compound exhibits superior bioavailability, allowing it to efficiently cross cell membranes and elevate intracellular NAD+ levels with minimal side effects such as flushing. As cellular NAD+ concentrations naturally decline with age, supplementation with Nicotinamide Riboside Chloride has emerged as a promising strategy for combating age-related metabolic dysfunction, mitochondrial impairment, and DNA damage.
The primary utility of this compound lies in its role in cellular energy metabolism and sirtuin activation. By boosting NAD+, it supports the function of sirtuins and PARPs, enzymes essential for maintaining genomic stability, regulating circadian rhythms, and promoting healthy aging. Consequently, it is widely utilized in the nutraceutical and dietary supplement industries to support cognitive health, enhance physical endurance, and improve metabolic rate. Research suggests potential benefits in managing conditions associated with low NAD+ levels, including neurodegenerative diseases, cardiovascular issues, and insulin resistance. In the pharmaceutical sector, it serves as a key intermediate for developing novel therapeutics targeting metabolic disorders and age-associated pathologies. Furthermore, its stability and solubility make it a preferred choice for formulation in capsules, tablets, and liquid supplements. While generally considered safe for human consumption at recommended dosages, ongoing clinical trials continue to validate its long-term efficacy and safety profile across diverse populations. As the anti-aging market expands, Nicotinamide Riboside Chloride remains a cornerstone ingredient, bridging the gap between basic nutrition and advanced cellular repair mechanisms to promote overall vitality and longevity.