Product Description
NGR peptide is a cell penetrating peptide containing an asparagine-glycine-arginine (NGR) sequence. NGR peptide can target the CD13 receptor specifically overexpressed in tumor neovascular epithelial cells.NGR peptide can selectively bind to APN/CD13, can be immunocaptured or expressed on the cell surface, and NGR peptide has the greatest tumor selectivity. The anti-cancer drug doxorubicin (DOX) conjugated with NGR peptide exhibits higher anti-tumor effects and even lower toxicity than the free drug itself.In vivo NGR peptide imaging can not only provide more information about the NGR targeting process, including biodistribution and pharmacokinetics, but also reveal angiogenic activity related to tumor progression and malignant tumors.