Product Description
N-Arachidonoyl serotonin
Type : griffonia seed extract
Appearance :powder
Part : seed
Extraction Method : Solvent Extraction
Packing : bottle , drum , vacuum packed
Grade :medicine grade
Molecular formula : N30H42N2O2
Function :
1. Inhibitors of fatty acid amide hydrolase (FAAH).
2. It has analgesic effect on rodents.
Contact :
Trading manger : Helen Tan
Whatsapp : +86 13930229229
Website : www.blrhbio.com
AI Product Description
*The following content is generated by AI and is for reference only.
N-Arachidonoyl serotonin (AA-5HT), identified by CAS number 187947-37-1, is a specialized bioactive lipid mediator belonging to the class of N-acylethanolamines. Structurally, it is formed through the amide linkage between arachidonic acid and serotonin. This compound functions as a potent endogenous ligand for various receptors, including the transient receptor potential vanilloid 1 (TRPV1) channel and potentially cannabinoid receptors, although its affinity for CB1 and CB2 is generally lower than that of anandamide. AA-5HT plays a significant role in modulating pain perception, inflammation, and vascular tone within the central and peripheral nervous systems.
In scientific research, AA-5HT is primarily utilized as a valuable tool for investigating the mechanisms of nociception and neuroinflammation. Researchers employ this substance to study TRPV1 signaling pathways, which are critical for understanding chronic pain conditions and developing novel analgesics. Furthermore, its unique structure allows scientists to explore the cross-talk between serotonergic and endocannabinoid systems, offering insights into how these pathways regulate mood, appetite, and cardiovascular function. Due to its complex synthesis and rapid metabolism in biological systems, AA-5HT is typically sourced from chemical suppliers for in vitro assays or animal model studies rather than being used directly in clinical settings.
Handling this compound requires strict adherence to safety protocols. As a biologically active agent, it should be treated with caution to prevent unintended exposure. Laboratory personnel must wear appropriate personal protective equipment, including gloves, lab coats, and eye protection, when manipulating AA-5HT. Storage should occur at low temperatures, typically -20°C or below, in a dry, dark environment to maintain chemical stability and prevent degradation. It is essential to consult the specific Safety Data Sheet (SDS) provided by the manufacturer before use, as handling procedures may vary based on concentration and purity. While not currently classified as a controlled substance, its pharmacological activity necessitates responsible disposal according to institutional hazardous waste guidelines. Ultimately, AA-5HT remains a crucial molecule for advancing our understanding of lipid-mediated neurotransmission and therapeutic development.