Product Description
CAS No.:
131-48-6
Other Names:
N-Acetylsialic Acid
MF:
C11H19NO9
EINECS No.:
205-023-1
Grade Standard:
Cosmetic Grade, Food Grade, Medicine Grade, Pharm Grade
Usage:
Pharmaceuticals
Brand Name:FLAG
Model Number:
FHN026
Purity:
98%Min
Product name:
Sialic Acid
Appearance:
White to Off-white Powder
Assay:
98%
Molecular Formula:
C11H19NO9
Molecular Weight:
309.27
AI Product Description
*The following content is generated by AI and is for reference only.
N-acetylneuraminic acid, commonly abbreviated as Neu5Ac, is a fundamental sialic acid derivative that plays a pivotal role in biological systems. With the molecular formula C11H19NO9 and the CAS registry number 138-59-0, this compound serves as the predominant member of the sialic acid family found in vertebrates. Structurally, it consists of a nine-carbon backbone featuring an N-acetyl group at the C5 position and a carboxyl group at C1, which are critical for its unique chemical reactivity and biological function.
In nature, Neu5Ac is almost exclusively found as the terminal sugar residue on glycoproteins and glycolipids located on the cell surface. This strategic positioning allows it to mediate crucial cell-cell interactions, including immune system regulation, pathogen recognition, and cell signaling pathways. For instance, many viruses, such as influenza, utilize specific receptors containing Neu5Ac to attach to and infect host cells. Consequently, understanding the biochemistry of this molecule is essential for developing antiviral therapeutics and vaccines.
Beyond its physiological significance, N-acetylneuraminic acid has gained substantial attention in the pharmaceutical and biotechnology sectors. It is widely used as a standard reference material in analytical chemistry for identifying and quantifying sialic acids in complex biological samples. Furthermore, researchers employ it in the synthesis of novel glycoconjugates and synthetic vaccines designed to mimic natural cell surfaces. Its ability to modulate immune responses makes it a valuable candidate for immunomodulatory drug development. Additionally, recent studies suggest potential applications in cosmetic formulations, where it may help maintain skin barrier integrity and hydration levels by influencing cellular communication.
The production of high-purity Neu5Ac typically involves enzymatic conversion from precursors or extraction from natural sources like bovine submaxillary glands. As the field of glycobiology advances, the demand for this versatile molecule continues to grow, driving innovations in diagnostic tools, therapeutic agents, and functional food ingredients. Ultimately, N-acetylneuraminic acid remains a cornerstone compound in modern life sciences, bridging the gap between basic biochemical research and practical clinical applications.