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Other Specialized Reagents

N-Acetyl-L-norleucyl-L-alanyl-L-histid

Category:

Other Specialized Reagents

CAS NO:

448944-47-6

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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Hangzhou Go Top Peptide Biotech Co.,Ltd.

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Basic Info

CAS Number

448944-47-6

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Brand: Gutuo Appearance: white solid Storage: shading, cool and dry, sealed and stored Purity: ≥99% Main use: pharmaceutical intermediates Executive standard: enterprise standard Specification: 25kg/barrel or 1kg/bag (subject to customer requirements) Sales scope: nationwide

AI Product Description

*The following content is generated by AI and is for reference only.

N-Acetyl-L-norleucyl-L-alanyl-L-histidine is a specialized synthetic tripeptide derivative widely utilized in advanced biochemical research and pharmaceutical development. Chemically, this compound consists of an acetylated N-terminal norleucine residue linked via peptide bonds to L-alanine and terminating with L-histidine. Its molecular formula is C14H23N5O4, reflecting the precise arrangement of carbon, hydrogen, nitrogen, and oxygen atoms that define its structural integrity. While specific commercial catalogs may list varying CAS numbers depending on purity grades or salt forms, the core molecule serves as a critical model substrate for studying proteolytic enzyme kinetics, particularly those involving peptidases and amidases. The primary application of this tripeptide lies in enzymology, where it acts as a standardized substrate to evaluate the specificity and catalytic efficiency of various hydrolases. Researchers utilize it to investigate the cleavage mechanisms of histidine-containing peptides, which are often relevant in understanding metabolic pathways and protein degradation processes within biological systems. Furthermore, due to the presence of the imidazole ring in the histidine moiety, this compound exhibits unique coordination properties, making it valuable in studies concerning metal ion binding and chelation chemistry. In drug discovery contexts, analogs of this structure help scientists design inhibitors targeting specific protease enzymes associated with diseases such as cancer or viral infections. Beyond academic research, derivatives of similar peptide sequences are explored for potential therapeutic applications, including the development of targeted drug delivery systems or diagnostic agents. The stability and solubility characteristics of N-Acetyl-L-norleucyl-L-alanyl-L-histidine make it suitable for in vitro assays requiring high reproducibility. However, it is important to note that this substance is strictly intended for laboratory use and is not approved for human consumption or clinical treatment outside of controlled experimental settings. As with all peptide-based reagents, handling requires adherence to safety protocols to ensure researcher protection and sample integrity. Continued investigation into this molecule contributes significantly to our broader understanding of amino acid metabolism and enzyme-substrate interactions, fostering innovation in biotechnology and medicinal chemistry fields globally.