Brand: Gutuo Appearance: white solid Storage: shading, cool and dry, sealed and stored Purity: ≥99% Main use: pharmaceutical intermediates Executive standard: enterprise standard Specification: 25kg/barrel or 1kg/bag (subject to customer requirements) Sales scope: nationwide
*The following content is generated by AI and is for reference only.
N-Acetyl-D-alanine is a specialized chiral amino acid derivative widely utilized in the fields of pharmaceutical synthesis, biochemical research, and organic chemistry. Its molecular formula is C5H9NO3, and it is uniquely identified by the CAS Registry Number 1648-07-3. Unlike its L-isomer counterpart, which is commonly found in natural protein structures, N-Acetyl-D-alanine serves as a critical building block for constructing complex molecules that require specific stereochemical configurations.
The primary application of this compound lies in the development of novel antibiotics and peptide-based therapeutics. D-amino acids are increasingly recognized for their resistance to proteolytic degradation by common mammalian enzymes, making them ideal candidates for enhancing the metabolic stability of drug candidates. In bacterial cell wall biosynthesis, D-alanine residues are essential components; consequently, N-acetylated derivatives play a pivotal role in studying peptidoglycan assembly and developing inhibitors against resistant pathogens like methicillin-resistant Staphylococcus aureus (MRSA). Researchers frequently employ N-Acetyl-D-alanine as a standard reference material or a starting substrate in enzymatic assays designed to investigate the activity of alanine racemases and transpeptidases.
Beyond medicinal applications, this molecule is valuable in asymmetric synthesis and chiral resolution processes. It acts as a chiral auxiliary or a ligand precursor in the design of stereoselective catalysts. The acetyl group protects the amino functionality while maintaining the integrity of the carboxyl group, allowing for selective chemical modifications in multi-step synthesis pathways. Furthermore, it is used in the production of high-value fine chemicals where optical purity is paramount. Due to its distinct physicochemical properties, including solubility characteristics and thermal stability, N-Acetyl-D-alanine is often supplied in high purity grades suitable for analytical standards and industrial-scale production. Its versatility underscores its importance as a fundamental reagent in modern chemical biology and advanced materials science, bridging the gap between basic research and clinical application.