MOTS-c (human) is a kind of mitochondrial derived peptide (MDP). The main physiological function is to promote the biosynthesis of AICAR, an endogenous amp analogue, so as to promote amp activated protein kinase (AMPK), which can also enhance the induced cell demand for glucose uptake and improve insulin sensitivity. As a drug raw material, it is a potential weight-loss peptide raw material, and has a good anti-aging effect.