*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Methoxy PEG Thioctic Acid (MW 2000) is a bifunctional PEG derivative featuring a thiol-reactive lipoic acid moiety. It serves as a critical linker for conjugating drugs to PEG chains via disulfide bonds, enabling controlled release in reducing intracellular environments. <strong>Molecular Formula</strong>: C<sub>x</sub>H<sub>y</sub>N<sub>z</sub>O<sub>w</sub>S<sub>v</sub> (varies with PEG length). <strong>CAS No.</strong>: Typically unassigned specific number due to polydispersity.</p>
<h3>Application</h3>
<ul>
<li><strong>Drug Delivery Systems:</strong> Construction of cleavable PEG-drug conjugates for targeted cancer therapy.</li>
<li><strong>Bioconjugation:</strong> Labeling proteins or antibodies with fluorescent tags via thiol-maleimide chemistry.</li>
<li><strong>Nanomedicine:</strong> Functionalizing gold nanoparticles and liposomes for enhanced stability and circulation time.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent oxidation of the thiol group. Avoid contact with strong oxidizers. Use only in GMP-compliant facilities; not approved for direct clinical use without formulation validation.</p>