*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Methoxy PEG Carboxyl is a functionalized polyethylene glycol derivative used as a hydrophilic linker. The core synthesis involves etherification of PEG with methanol followed by carboxylation. <strong>Molecular Formula</strong>: C<sub>n</sub>H<sub>2n+4</sub>O<sub>n+1</sub>(COOH). <strong>CAS No.</strong>: Varies by MW (e.g., 25967-07-3 for mPEG-COOH, MW 5k).</p>
<h3>Application</h3>
<ul>
<li><strong>Drug Delivery</strong>: Conjugation to peptides and proteins to enhance circulation half-life.</li>
<li><strong>Nanomedicine</strong>: Surface modification of liposomes and polymeric micelles for targeted therapy.</li>
<li><strong>Diagnostic Imaging</strong>: Functionalization of contrast agents for MRI and fluorescence labeling.</li>
</ul>
<h3>Precautions</h3>
<p>Store in a cool, dry place below 25°C under inert atmosphere. Avoid moisture to prevent hydrolysis. Personal protective equipment (gloves, goggles) is mandatory during handling due to potential irritation risks.</p>