*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Maleimide PEG Hydroxyl</strong> is a bifunctional polyethylene glycol reagent featuring a maleimide group for thiol conjugation and a terminal hydroxyl group. Synthesized via ring-opening polymerization of ethylene oxide followed by functionalization, it serves as a critical linker in bioconjugation. Typical molecular formula: C<sub>n</sub>H<sub>2n+4</sub>O<sub>n</sub>S (varies by MW); CAS No.: varies by specific chain length.</p>
<h3>Application</h3>
<ul>
<li>Antibody-Drug Conjugates (ADCs) for targeted cancer therapy delivery.</li>
<li>PEGylation of therapeutic proteins to enhance pharmacokinetics.</li>
<li>Diagnostic imaging probes requiring stable maleimide-thiol attachment.</li>
<li>Biomaterial surface modification for controlled cell adhesion.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent hydrolysis. Avoid contact with moisture and strong oxidizers. Not approved for direct human injection without rigorous purification and regulatory clearance.</p>