Product Description
Human antimicrobial peptide LL-37 has strong antibacterial and anti-inflammatory activity, broad-spectrum antibacterial effect number, but due to its relatively large molecular weight, and low cell selectivity in the body, coupled with high production costs, it limits LL -37 Application in treatment. Therefore, a new short α-helical antimicrobial peptide derived from LL-37 was developed. This type of antimicrobial peptide with a shorter sequence has better cell selectivity, and compared with LL-37, its anti-inflammatory activity is not significantly lost. LL-37 FK-13 is one of the short α-helix antimicrobial peptides derived from LL-37. It consists of 13 amino acids and has high cell selectivity and anti-inflammatory activity. Studies have shown that LL-37 FK-13 can kill microbial cells by penetrating the cell membrane and destroying the integrity of the membrane.