LL-37 is the only antibacterial peptide in vivo that can neutralize endotoxin. In vitro, LL-37 can prevent endotoxin from binding to macrophages and inhibit endotoxin-induced tumor necrosis factor-α (TNF-α) expression. In animal simulation experiments, LL-37 can reduce the mortality of endotoxin shock model rats, mainly because LL-37 can combine with the negatively charged groups in endotoxin, inhibit the toxic transformation of endotoxin, and eliminate The effect of toxin biological activity. LL-37 (37-1) is a peptide with the reverse sequence of LL-37. It consists of 37 amino acids and has similar biological functions.