1H-Purine-2,6-dione,7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-8-(methylamino)-1-[(4-methyl-2-quinazolinyl)methyl]-;7-(But-2-yn-1-yl)-3-methyl-8-(methylamino)-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dChemicalbookione(LinagliptinImpurity);LinagliptinImpurity49Q:WhatisLinagliptinImpurity49Q:WhatistheCASNumberofLinagliptinImpurity49;LinagliptinImpurity128;LinagliptinImpurity149;LinagliptinImpurity71CRS;LinagliptinImpurity71
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<h3>Overview</h3>
<p>Linagliptin Impurity V is a critical synthetic intermediate in the pharmaceutical manufacturing of the dipeptidyl peptidase-4 inhibitor. This compound serves as a reference standard for quality control and method development. Its chemical identity is defined by the molecular formula <strong>C28H36N6O5</strong> and CAS number <strong>1097765-47-7</strong>.</p>
<h3>Application</h3>
<ul>
<li>Quality assurance testing in API production facilities.</li>
<li>Validation of analytical methods such as HPLC and LC-MS.</li>
<li>Stability-indicating studies for drug substance degradation profiling.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly limit human exposure during handling; use appropriate PPE including respirators and nitrile gloves. Store under inert atmosphere at temperatures between 2°C and 8°C to prevent hydrolysis or oxidation. Do not use for clinical therapeutic purposes directly.</p>