Brand: Gutuo Appearance: white solid Storage: shading, cool and dry, sealed and stored Purity: ≥99% Main use: pharmaceutical intermediates Executive standard: enterprise standard Specification: 25kg/barrel or 1kg/bag (subject to customer requirements) Sales scope: nationwide
*The following content is generated by AI and is for reference only.
L-Alanine methyl ester hydrochloride is a valuable chiral building block widely utilized in organic synthesis and pharmaceutical research. With the molecular formula C4H10ClNO2 and CAS number 3675-89-6, this compound serves as a protected form of the essential amino acid L-alanine. The presence of the methyl ester group enhances its solubility in organic solvents, while the hydrochloride salt ensures stability and ease of handling during storage and transportation.
Primarily employed in peptide chemistry, this reagent acts as a key intermediate for the efficient synthesis of dipeptides, tripeptides, and complex polypeptide structures. Its activated carboxyl group facilitates rapid coupling reactions with various amines under mild conditions, minimizing racemization risks that often plague standard amino acid derivatives. Consequently, it is indispensable for producing bioactive compounds, including antibiotics, enzyme inhibitors, and potential anticancer agents. Researchers frequently utilize L-alanine methyl ester hydrochloride to construct specific stereochemical configurations required for biological activity studies.
Beyond peptide assembly, this compound finds applications in material science for developing functional polymers and in agrochemical research for creating novel herbicides or growth regulators. The hydrochloride form improves crystallinity, allowing for straightforward purification via recrystallization, which is critical for achieving high purity standards demanded by regulatory bodies in drug development. Furthermore, its compatibility with solid-phase synthesis protocols makes it a preferred choice for automated peptide synthesizers used in high-throughput screening laboratories.
Safety data indicates that while generally stable, the substance should be handled with appropriate personal protective equipment due to its acidic nature. Proper storage in a cool, dry environment prevents degradation. As the demand for precise chiral molecules grows in the biopharmaceutical sector, L-alanine methyl ester hydrochloride remains a cornerstone reagent, bridging the gap between simple chemical precursors and sophisticated therapeutic candidates. Its versatility underscores its importance in advancing both academic research and industrial manufacturing processes across diverse scientific disciplines.