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CAS NO:
39825-33-7
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Basic Info
CAS Number
39825-33-7
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Product Description
Brand: Gutuo Appearance: white solid Storage: shading, cool and dry, sealed and stored Purity: ≥99% Main use: pharmaceutical intermediates Executive standard: enterprise standard Specification: 25kg/barrel or 1kg/bag (subject to customer requirements) Sales scope: nationwide
AI Product Description
*The following content is generated by AI and is for reference only.
L-Alanine, 1-methylethyl ester is a valuable chiral building block widely utilized in organic synthesis and pharmaceutical research. Chemically known as L-alanine isopropyl ester, this compound features an amino acid backbone where the carboxylic acid group is protected by an isopropyl moiety. Its molecular formula is C6H13NO2, and it carries the CAS registry number 2748-09-2. The structure consists of a central alpha-carbon bonded to a methyl group, an amino group, and an isopropyl ester linkage, preserving the natural L-configuration essential for biological compatibility.
The primary utility of L-Alanine, 1-methylethyl ester lies in its role as a protected amino acid derivative during peptide synthesis. In solid-phase and solution-phase chemistry, protecting groups are critical to prevent unwanted side reactions at reactive sites. The isopropyl ester serves as an effective temporary protection for the carboxyl functionality, allowing chemists to selectively couple the amine group with other activated species without interference. This specificity ensures high fidelity in constructing complex polypeptide chains and peptidomimetics. Furthermore, the isopropyl group offers distinct advantages regarding steric bulk and stability compared to simpler alkyl esters like methyl or ethyl, often facilitating easier purification processes through crystallization or chromatography.
Beyond peptide assembly, this reagent finds applications in the development of novel drug candidates and bioactive molecules. Researchers employ it to synthesize specific amino acid analogs that may exhibit improved metabolic stability or altered pharmacokinetic profiles. Its chirality makes it indispensable for creating enantiomerically pure compounds, a requirement in modern drug discovery to avoid toxic effects associated with racemic mixtures. Additionally, the compound can serve as a precursor for various heterocyclic structures and specialized intermediates in fine chemical manufacturing. Due to its stability under standard laboratory conditions and ease of deprotection using mild acidic hydrolysis, L-Alanine, 1-methylethyl ester remains a staple reagent in academic and industrial laboratories dedicated to medicinal chemistry and materials science. It bridges the gap between simple amino acids and complex therapeutic agents, enabling precise molecular engineering.
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