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<h3>Overview</h3>
<p><strong>Imatinib-d8</strong> is a deuterated stable isotope internal standard for <strong>mass spectrometry</strong> quantification of the kinase inhibitor Imatinib. Synthesized via isotopic substitution, it ensures high accuracy in pharmacokinetic studies. Molecular formula: C<sub>29</sub>H<sub>30</sub>D<sub>8</sub>N<sub>5</sub>O; CAS No.: 1207646-78-1.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmacokinetics:</strong> Serves as an internal standard for LC-MS/MS bioanalysis to measure plasma concentrations.</li>
<li><strong>Clinical Trials:</strong> Validates assay precision and recovery rates during drug metabolism research.</li>
<li><strong>Quality Control:</strong> Calibrates analytical instruments in pharmaceutical manufacturing environments.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent degradation. Handle with appropriate PPE to avoid skin contact. Intended strictly for laboratory research use only, not for clinical administration.</p>