*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Hydroxyl PEG12 Carboxyl</strong> is a monofunctional polyethylene glycol derivative featuring terminal hydroxyl and carboxylic acid groups. Synthesized via ring-opening polymerization of ethylene oxide followed by functionalization, it serves as a critical linker in bioconjugation. Molecular formula: C26H54O14; CAS No.: 88077-60-9.</p>
<h3>Application</h3>
<ul>
<li>Drug delivery systems for antibody-drug conjugates (ADCs)</li>
<li>Polymer therapeutics requiring controlled release profiles</li>
<li>Diagnostics as surface modifiers for protein immobilization</li>
<li>Nanoparticle functionalization to enhance biocompatibility</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at 2-8°C to prevent hydrolysis. Avoid direct skin contact during handling. Not approved for direct clinical injection without validated purification protocols.</p>