*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Hydroxyl PEG12Amine</strong> is a heterobifunctional polyethylene glycol derivative featuring a terminal hydroxyl group and a primary amine. Synthesized via controlled ring-opening polymerization of ethylene oxide followed by functionalization, it serves as a critical linker in bioconjugation. Molecular formula: C<sub>26</sub>H<sub>55</sub>NO<sub>13</sub>. CAS No.: 89074-43-3.</p>
<h3>Application</h3>
<ul>
<li>Antibody-Drug Conjugates (ADCs) for targeted cancer therapy delivery.</li>
<li>PEGylation of therapeutic proteins to enhance serum half-life.</li>
<li>Synthesis of dendrimers and polymer-drug conjugates.</li>
<li>Bioconjugation scaffolds for diagnostic imaging agents.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent oxidation. Avoid contact with skin and eyes; use appropriate PPE. Not intended for direct clinical administration without formulation into approved drug products.</p>