H-Gly-Pro-Gly-NH2 is a short peptide fragment composed of three amino acids. The C-terminus of the sequence is blocked by an amide bond, and the N-terminus is exposed with an amino group. Studies have shown that H-Gly-Pro-Gly-NH2 can inhibit the replication of HIV-1 through its metabolite α-hydroxyglycineamide, which can increase the antiviral effect of drugs such as zidovudine and ritonavir.