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CAS NO:
84418-43-9
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Basic Info
CAS Number
84418-43-9
Pharmacopoeia
In-house Standards
Grade
Research grade
Is Manufacturer
No
Packaging & Delivery
Packaging Specification
5g,10g,25g,50g,100g,500g
Minimum Order Quantity
5g
Delivery Cycle
In stock or 1-2weeks
Product Description
Hangzhou Go Top Peptide Biotech Co.,Ltd. - a reliable supplier of peptides synthesis.Our clients include * the pharma, cosmetic and biotech companies and research institutions worldwide. Welcome to contact us by email to sales37@gotopbio.com
AI Product Description
*The following content is generated by AI and is for reference only.
Fmoc-NH2, chemically known as 9-Fluorenylmethoxycarbonylamine, is a specialized reagent widely utilized in the field of peptide synthesis and organic chemistry. Its primary function serves as a protecting group for amino groups, ensuring precise control during the stepwise assembly of complex peptide structures. The molecular formula of Fmoc-NH2 is C16H15NO3, and it is uniquely identified by the CAS number 24870-83-3. This compound features a fluorenylmethyloxycarbonyl moiety attached to an amine, providing stability under various reaction conditions while remaining easily removable under mild basic conditions, typically using piperidine or diethylamine.
In laboratory settings, Fmoc-NH2 is indispensable for solid-phase peptide synthesis (SPPS). Unlike the traditional Boc strategy, the Fmoc approach offers superior compatibility with acid-sensitive side chains and functional groups, making it the preferred method for synthesizing long, complex peptides and proteins. Researchers employ this reagent to protect the N-terminal amine of amino acids, preventing unwanted side reactions such as cyclization or polymerization during coupling steps. Once the desired sequence is assembled, the Fmoc group can be cleaved efficiently without affecting other sensitive moieties within the molecule.
Beyond standard peptide manufacturing, Fmoc-NH2 finds applications in the development of peptidomimetics, drug delivery systems, and bioconjugation technologies. Its ability to facilitate high-yield reactions with minimal racemization ensures the production of biologically active compounds with high purity. Furthermore, the versatility of Fmoc chemistry allows for the synthesis of cyclic peptides and modified amino acids used in pharmaceutical research and diagnostics. As a cornerstone of modern synthetic methodology, Fmoc-NH2 continues to drive innovation in medicinal chemistry, enabling scientists to explore new therapeutic avenues and understand protein functions at a molecular level. Its reliability and ease of use have cemented its status as an essential tool in both academic research and industrial pharmaceutical production worldwide.
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Copyright 2006-2025 (All Rights Reserved)
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